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Better diagnosis and treatment for Sjögren’s syndrome

Common symptoms of Sjögren’s syndrome are a dry mouth and trouble swallowing. It is estimated that about 0.05 per cent of the population, mostly women, suffer from the illness. (Photograph: file404/Shutterstock)

Tue. 19 May 2015

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BERGEN, Norway: Muscle pain, fatigue, a dry mouth and trouble swallowing—these are the most common symptoms in Sjögren’s syndrome patients. From 19 to 22 May, leading scientists and patient organisations will focus on the disease, named after Swedish ophthalmologist Henrik Sjögren, at the 13th International Symposium on Sjögren’s Syndrome in Bergen.

Even though it is one of the most common chronic rheumatic inflammatory diseases, little is known about the syndrome. According to the event organiser, the condition may be as common as lupus, another chronic rheumatic disorder. Although the cause of Sjögren’s syndrome is unknown, it is believed to be influenced by a combination of genetic, environmental, and other factors. It is estimated that about 0.05 per cent of the population, mostly women, suffer from it, but owing to a lack of knowledge about the illness many people might not realise that they have it.

“The disease affects the glands in the body, particularly the tear glands and the salivary glands, resulting in decreased production of tears and saliva. However, since the symptoms are so diverse and common, it often takes a long time before patients are diagnosed correctly,” said Prof. Roland Jonsson, head of the Broegelmann Research Laboratory at the Department of Clinical Science of the University of Bergen.

A key issue on the symposium’s agenda is the recent testing of biological medicines to treat the disease. Other than that, there is no cure for the illness. “Consequently, the treatment focuses on relieving symptoms and pain,” Jonsson said.

The symposium aims to discuss the latest scientific findings and research projects in order to improve the understanding and thereby help to enhance the diagnosis and treatment of the disease. The scientific programme features lectures on autoantibodies, new biomarkers, classification criteria, as well as new diagnostic tools and personalised therapies.

About 250 participants from around the world, including several patients with Sjögren’s syndrome who will be taking part in research projects, are expected to attend the biannual event at the Radisson Blu Royal Hotel in Bryggen in Bergen. The organisers hope that the meeting will promote worldwide networking between disciplines such as immunology, rheumatology, pathology, ophthalmology and dentistry in the future.

More information can be found at www.sicca.org.

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